O-083. Parental imprinting in normal and abnormal growth
نویسندگان
چکیده
منابع مشابه
Genetic conflict in early development: parental imprinting in normal and abnormal growth.
Parental (genomic) imprinting is the process by which the differential expression of maternal and paternal alleles at certain genetic loci in mammalian embryos occurs. Such loci are implicated in the control of fetal, placental and neonatal growth, and, more generally, in diverse aspects of fetal nutrient acquisition and maternal-fetal interactions. Not surprisingly, the aberrant expression of ...
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Genomic imprinting is the phenomenon whereby some genes preferentially produce mRNA transcripts from the gene copy derived from the parent of a specific sex. It has been implicated in a number of human diseases (most of them of endocrine interest), such as Prader-Willi/Angelman syndromes, Silver-Russell syndrome, Beckwith-Wiedemann syndrome, transient neonatal diabetes, the focal form of nesidi...
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Human placental growth hormone (PGH), encoded by the growth hormone (GH) variant gene on chromosome 17, is expressed in the syncytiotrophoblast and extravillous cytotrophoblast layers of the human placenta. Its maternal serum levels increase throughout pregnancy, and gradually replaces the pulsatile secreted pituitary GH. PGH is also detectable in cord blood and in the amniotic fluid. This plac...
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.................................................................................... 5 ABBREVIATIONS .......................................................................... 7 FOREWORD ................................................................................... 9 INTRODUCTION .......................................................................... 10 GENERAL ASPECTS ON GROWTH REGULAT...
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reference electrode (3). The ionized calcium concentration of sequential retentates prepared by ultrafiltration of a human control serum increased with increasing protein concentration in a way consistent with Donnan theory (4, 5) when the analyzers’ standard reference-electrode liquid junctionswere used; however, the ionized calcium in the same retentates declined slightly with increasing prot...
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ژورنال
عنوان ژورنال: Human Reproduction
سال: 1999
ISSN: 1460-2350,0268-1161
DOI: 10.1093/humrep/14.suppl_3.45-a